Delivering Drugs to the Right Place
MCDB professor Thomas Weimbs and his team have developed a targeted drug delivery method that could potentially slow the progression of polycystic kidney disease. Weimbs and his team have found a method that enables a class of antibodies, immunoglobulin-A (IgA), to penetrate the cyst walls in PKD kidneys. The strategy opens up the possibility of repurposing a large number of existing drugs for PKD therapy. The researchers’ results appear in the Journal of Biological Chemistry.