MCDB team discovers how to change cell types by flipping a single switch

Dec 3, 2013

With few exceptions, cells don’t change type once they have become specialized — a heart cell, for example, won’t suddenly become a brain cell. However, new findings by researchers directed by MCDB professor Joel Rothman have identified a method for changing one cell type into another in a process called forced transdifferentiation. Their work appears today in the journal Development.

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