UCSB Eye Researchers to Develop Mouse Model of Retinal Disease
UCSB researchers led by MCDB scientist Steven Fisher have been awarded a grant from the Macula Vision Research Foundation to develop a mouse model of the eye disease central serous chorioretinopathy (CSR). In humans with this disease, abnormal fluid accumulation leads to retinal detachment. Recently, a mouse strain was identified that spontaneously develops serous retinal detachment similar to the human disease. Fisher and his collaborators will characterize the cellular and molecular changes occuring in this mouse model of CSR. Understanding the underlying mechanisms may suggest novel approaches to treatment of patients with CSR.